12-acetoxy-1-acetyl-8-((5-((3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-10a,12a-dimethyltetradecahydro-1H-cyclopenta[1,2]phenanthro[1,10a-b]oxiren-11-yl 2-methylbutanoate - Names and Identifiers
Name | Tenacissoside H
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Synonyms | Tenacissoside H Tenacissimoside C Tenacissoside H (Tenacissimoside C) Pregnan-20-one, 12-(acetyloxy)-3-[[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-β-D-allopyranosyl)-3-O-methyl-β-D-arabino-hexopyranosyl]oxy]-8,14-epoxy-11-(2-methyl-1-oxobutoxy)-, (3β,5α,11α,12β,14β,17α)- (3beta,5alpha,11alpha,12beta,14beta,17alpha)-12-(Acetyloxy)-3-[[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-beta-D-allopyranosyl)-3-O-methyl-beta-D-arabinohexopyranosyl]oxy]-8,14-epoxy-11-(2-methyl-1-oxobutoxy)pregnan-20-one 12-acetoxy-1-acetyl-8-((5-((3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-10a,12a-dimethyltetradecahydro-1H-cyclopenta[1,2]phenanthro[1,10a-b]oxiren-11-yl 2-methylbutanoate
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CAS | 191729-45-0
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12-acetoxy-1-acetyl-8-((5-((3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-10a,12a-dimethyltetradecahydro-1H-cyclopenta[1,2]phenanthro[1,10a-b]oxiren-11-yl 2-methylbutanoate - Physico-chemical Properties
Molecular Formula | C42H66O14
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Molar Mass | 794.97 |
Density | 1.26 |
Melting Point | 196-200°C |
Boling Point | 815.4±65.0 °C(Predicted) |
Specific Rotation(α) | -82.0°(methanol) |
Solubility | Soluble in water, methanol, insoluble in petroleum ether. |
Appearance | White powder |
Color | White |
pKa | 12.89±0.70(Predicted) |
Storage Condition | Hygroscopic, -20°C Freezer, Under inert atmosphere |
MDL | MFCD22125017 |
Physical and Chemical Properties | White powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from customs vine. |
12-acetoxy-1-acetyl-8-((5-((3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-10a,12a-dimethyltetradecahydro-1H-cyclopenta[1,2]phenanthro[1,10a-b]oxiren-11-yl 2-methylbutanoate - Risk and Safety
Safety Description | 24/25 - Avoid contact with skin and eyes.
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HS Code | 29389090 |
12-acetoxy-1-acetyl-8-((5-((3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-10a,12a-dimethyltetradecahydro-1H-cyclopenta[1,2]phenanthro[1,10a-b]oxiren-11-yl 2-methylbutanoate - Introduction
Tenacissoside H, also known as sinomenine H, is a natural product widely found in lianas. The following is a description of the nature, use, formulation and safety information of Tenacissoside H:
1. Nature:
Tenacissoside H is a yellow solid, soluble in organic solvents such as ethanol and chloroform. It has a bitter taste, a crystallization temperature of 150-151 ° C., and a melting point of 165-166 ° C.
2. Use:
Tenacissoside H is a natural drug with a variety of biological activities such as anti-inflammatory, antioxidant and immunomodulatory. It is widely used in the development and production of traditional Chinese medicine and health products for the treatment of inflammatory diseases, muscle and bone pain and cancer. In addition, Tenacissoside H can also be used in cosmetics and other fields.
3. Preparation method:
Tenacissoside H is mainly obtained by extracting it from vines. General extraction methods include ultrasonic extraction, leaching, distillation, etc. After extraction, pure Tenacissoside H was obtained by the steps of crystallization, extraction and purification.
4. Safety Information:
Tenacissoside H is a natural product, but it should be used with caution. In the process of use, the following matters should be paid attention:
-Avoid contact with eyes, such as accidental contact, should immediately rinse with plenty of water.
-Avoid inhalation and ingestion during use.
-If an allergic reaction or other discomfort occurs, you should immediately stop using it and consult your doctor's advice.
-Please store out of reach of children.
-During storage and transportation, avoid high temperature and humid environment.
Last Update:2024-04-09 15:16:35